Senior Scientist – Immunology and biotherapeutics

About the role

Active Novartis Workday posting REQ-10086253, on-site Cambridge, full-time. Posted 12 days ago with an active Apply button. Senior scientist role focused on human immunology, immune profiling, disease-relevant multicellular assays, immune activation/cytokine release, primary-cell and multicolor FACS assays, qPCR/transcriptomics/immunoassays, translational biomarkers, and early safety risk assessment. Working knowledge of xRNA/AOC is desirable, not essential.

Requirements

• PhD in life science, preferably immunology or cell biology, or MSc plus 2-5 years research experience
• Deep expertise in human immunology and immune assay development, preferably primary immune cells, multicellular assays, tissue-relevant models or disease-relevant ex vivo platforms
• Experience assessing immunogenicity, immune activation, cytokine release, anti-drug immune responses or immune-related biologic liabilities
• Proficiency with flow cytometry, immunoassays, qPCR, transcriptomics or imaging

What you'll do

• Design and execute immunology profiling strategies for immune-cell activation, modulation, cytokine release, innate sensing, adaptive responses, and disease-relevant outcomes
• Execute and analyze complex primary-cell assays, multicolor FACS, and functional immunological assays
• Generate mechanistic data to support candidate optimization, translational biomarkers, safety risk assessment, and discovery/early development decisions
• Collaborate with immunology, disease biology, antibody engineering, bioanalytics, toxicology and translational medicine teams
• Present results and prepare reports

Where this was posted

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